Proteomics

News and Updates

Woman uses gas analysis mass spectrometer at NBS for chemical analysis of gas or vapor mixtures

NIST Adds New 'Fingerprints' to Chemical Identification Database

June 17, 2020

The National Institute of Standards and Technology (NIST) has updated its database of chemical fingerprints, called mass spectra, that are used to identify

A Solution to a Hairy Problem in Forensic Science

November 5, 2019

In an effort to make hair comparison a more useful technique for investigating crimes, scientists at the National Institute of Standards and Technology (NIST)

How the Cone Snail’s Deadly Venom Can Help Us Build Better Medicines

October 10, 2017

Cone snails have inspired humans for centuries. Coastal communities have often traded their beautiful shells like money and put them in jewelry. Many artists

Projects and Programs

Trusted AI framework for a new class of Standard Reference Materials and Data with exquisitely characterized uncertainty for billions of properties

A new collaboration between NIST's Human Genomics Team, Mass Spectrometry Data Center, and Information Technology Laboratory to use and develop artificial

NIST Urine Albumin Standardization Program

The NIST Urine Albumin Standardization Program is focused on the development of a measurement procedure and reference materials to support an international

Performance Metrics for Proteomics

In collaboration with the National Cancer Institute's Clinical Proteomic Technologies for Cancer (CPTC), NIST researchers are developing specific and

Comparative Serum Proteomics Project

Initially the Comparative Mammalian Proteome Aggregator Resource (CoMPARe) Program will generate proteomic data from sera from 25 different species that

Publications

Liver proteome response to torpor in a basoendothermic mammal, Tenrec ecaudatus, provides insights into the evolution of homeothermy

October 6, 2021

Author(s)

Jane Khudyakov, Michael Treat, Mikayla Shanafelt, Jared Deyarmin, Ben Neely, Frank van Breukelen

Many mammals use adaptive heterothermy (e.g., torpor, hibernation) to reduce metabolic demands of maintaining high body temperature (Tb). Torpor is typically

Quantitative proteomic analysis for evaluating affinity isolation of extracellular vesicles

September 28, 2021

Author(s)

Ai Nguyen, Tingting Wang, Illarion Turko

Absolute quantification with mass spectrometry and isotope labelled internal standards has found broad applications in biomedical research. In the present

Rewinding the Molecular Clock: Looking at Pioneering Molecular Phylogenetics Experiments in the Light of Proteomics

September 15, 2021

Author(s)

Ben Neely, Magnus Palmblad

Science is full of overlooked and undervalued research waiting to be rediscovered. Proteomics is no exception. In this perspective, we follow the ripples from a

Nanopore sensing: a physical-chemical approach

September 1, 2021

Author(s)

Joseph W. Robertson, Madhav Ghimire, Joseph Reiner

Protein nanopores have emerged as an important class of sensor, for the understanding of biophysical processes, such as molecular transport across membranes