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Description: A faster version of pedigree programs of Linkage
Fastlink is much faster than the original Linkage but does not
implement all the programs.
Description: faster version of pedigree programs of Linkage
Genetic linkage analysis is a statistical technique used to map
genes and find the approximate location of disease genes. There
was a standard software package for genetic linkage called
LINKAGE. FASTLINK is a significantly modified and improved
version of the main programs of LINKAGE that runs much faster
sequentially, can run in parallel, allows the user to recover
gracefully from a computer crash, and provides abundant new
documentation. FASTLINK has been used in over 1000 published
genetic linkage studies.
.
This package contains the following programs:
ilink: GEMINI optimization procedure to find a locally
optimal value of the theta vector of recombination
fractions
linkmap: calculates location scores of one locus against a
fixed map of other loci
lodscore: compares likelihoods at locally optimal theta
mlink: calculates lod scores and risk with two of more loci
unknown: identify possible genotypes for unknowns
--- 44559 Thu Jan 1 00:00:00 1970
+++ 89950 Thu Jan 1 00:00:00 1970
@@ -1,3 +1,20 @@
-A faster version of pedigree programs of Linkage
+faster version of pedigree programs of Linkage
- Fastlink is much faster than the original Linkage but does not
+ Genetic linkage analysis is a statistical technique used to map
- implement all the programs.
+ genes and find the approximate location of disease genes. There
+ was a standard software package for genetic linkage called
+ LINKAGE. FASTLINK is a significantly modified and improved
+ version of the main programs of LINKAGE that runs much faster
+ sequentially, can run in parallel, allows the user to recover
+ gracefully from a computer crash, and provides abundant new
+ documentation. FASTLINK has been used in over 1000 published
+ genetic linkage studies.
+ .
+ This package contains the following programs:
+ ilink: GEMINI optimization procedure to find a locally
+ optimal value of the theta vector of recombination
+ fractions
+ linkmap: calculates location scores of one locus against a
+ fixed map of other loci
+ lodscore: compares likelihoods at locally optimal theta
+ mlink: calculates lod scores and risk with two of more loci
+ unknown: identify possible genotypes for unknowns