# Source: eigensoft
# Package: eigensoft
# Versions: eigensoft (6.1.2+dfsg-1), eigensoft (6.1.3+dfsg-1), eigensoft (6.1.4+dfsg-1), eigensoft (6.1.4+dfsg-1+b1), eigensoft (6.1.4+dfsg-1+b2), eigensoft (7.2.1+dfsg-1), eigensoft (7.2.1+dfsg-1+b1), eigensoft (7.2.1+dfsg-2), eigensoft (7.2.1+dfsg-3), eigensoft (7.2.1+dfsg-3+b1), eigensoft (7.2.1+dfsg-3+b2), eigensoft (8.0.0+dfsg-1), eigensoft (8.0.0+dfsg-2), eigensoft (8.0.0+dfsg-2+b1), eigensoft (8.0.0+dfsg-2+b2)
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Description: reduction of population bias for genetic analyses
 The EIGENSOFT package combines functionality from the group's population
 genetics methods (Patterson et al. 2006) and their EIGENSTRAT stratification
 method (Price et al. 2006). The EIGENSTRAT method uses principal components
 analysis to explicitly model ancestry differences between cases and
 controls along continuous axes of variation; the resulting correction is
 specific to a candidate marker's variation in frequency across ancestral
 populations, minimizing spurious associations while maximizing power to
 detect true associations. The EIGENSOFT package has a built-in plotting
 script and supports multiple file formats and quantitative phenotypes.
Description-da: Reduktion af befolkningsbias for genetiske analyser
 Pakken EIGENSOFT kombinerer funktionalitet fra gruppens befolkningsgenetiske metoder (Patterson et al. 2006) og deres
 EIGENSTRAT-startifikationsmetode (Price et al. 2006). Metoden EIGENSTRAT
 bruger principielle komponentanalyse til eksplicit at vise
 forfaderforskelle mellem tilfælde og kontroller langs fortsættende akser af
 variation; den medfølgende korrektion er specifik til en kandidats markørs
 variation i frekvens på tværs af forfaderbefolkninger, minimerer uægte
 associationer mens funktionen for detektion af korrekte associationer
 forstærkes. Pakken EIGENSOFT har et indbygget plotskript og understøtter
 flere filformater og kvantitative fænotyper.

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